Yes you absolutely can, and we can help! Bullets follow very predictable trajectories governed by the laws of physics. The calculations which predict where a bullet will impact are no different for cannon balls or golf balls, and there are a lot of apps which can help you calculate this. As long as you know the bullet weight (typically measured in grains) and the velocity as it leaves the muzzle (usually written on the side of the box), you can determine where to sight-in at 25 yards so the round is zeroed exactly where you want it. For example, a standard 30-06 rifle sighted to 25 yards will also be dead nuts at 240 yards. Don’t believe it? Check out this article from American Hunter.